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Hearts can get 'younger' with physical activity

By Tom Walker    30 Dec 2018
The finding suggest that regular exercise may provide protection against the risk of future heart failure

People who take up exercise in their later years – regardless of their previous activity levels – are able to considerably improve their heart health through physical activity.

A study, published in the American Heart Association's journal, Circulation, found that two years of exercise improved maximal oxygen uptake and decreased cardiac stiffness in previously sedentary healthy middle-aged adults.

The finding suggests that regular exercise may provide protection against the risk of future heart failure.

Poor fitness in middle age is a risk factor for heart failure, particularly heart failure with a preserved ejection fraction (HFpEF).

The development of HFpEF has been linked with increased left ventricular (LV) stiffness, a consequence of sedentary ageing.

The study was based on 61 healthy, sedentary, middle-aged (aged 48-58) participants who were randomly assigned to either two years of exercise training or a control group without exercise.

The participants' LV end-diastolic pressure-volume relationships and LV stiffness – as well as calculate maximal oxygen uptake (Vo2max) – were then assessed during and after the study,

The 34 people who took part in the two-year exercise regime saw their Vo2max increase by 18 per cent, while the 27-strong control group saw their Vo2max decrease slightly.

LV stiffness in the exercise group was also reduced, whereas there was no change in the non-exercise group.

American Heart Association  Circulation 
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